Mikanda ya maginito imagwiritsidwa ntchito kwambiri pozindikira matenda a chitetezo chamthupi, kuzindikira ma cell, kuyeretsa mapuloteni, kusanja ma cell, ndi zina.
Immunodiagnosis: Mikanda ya Immunomagnetic imapangidwa ndi maginito particles ndi zipangizo ndi magulu ogwira ntchito.Mapuloteni ligand (ma antigen kapena ma antibodies) amalumikizidwa molumikizana ndi magulu ogwira ntchito a mikanda ya maginito, ndiyeno immunoassay imachitika pogwiritsa ntchito ma protein a maginito a mikanda.
Molecular diagnosis (nucleic acid m'zigawo): Nanoscale maginito mikanda ndi pamwamba magulu kuti adsorb nucleic asidi akhoza kulekanitsidwa ndi adsorbed ndi maginito, ndiyeno eluted kupeza template nucleic acid.
Kuyeretsedwa kwa mapuloteni: Agarose yolumikizidwa mwamphamvu pamodzi ndi mapuloteni ophatikizananso A/G pamwamba pa mikanda ya maginito, mapuloteni omangira a ProteinA/G, ndipo pamapeto pake amachotsedwa kuti apeze ma antibodies oyeretsedwa.
Kuzindikira kwa Immune ndi Kuzindikira kwa Maselo:
Chimodzi mwazofunikira za mikanda ya maginito ndikuzindikira matenda a chitetezo chamthupi, pomwe akhala zida zofunika kwambiri zowunikira matenda molondola.Makhalidwe apadera a mikanda ya maginito amachokera ku kuthekera kwawo kugwira ndikulekanitsa ma antigen kapena ma antibodies ku zitsanzo za odwala, kufewetsa njira yodziwira matenda.Pophatikizana mwamphamvu ma protein ligands, monga ma antigen kapena ma antibodies, kumagulu ogwira ntchito a mikanda ya maginito, ofufuza amatha kupanga ma immunoassay moyenera komanso molondola kwambiri.Njira inanso yochititsa chidwi yozindikira matenda a maselo, imapindula kwambiri pogwiritsa ntchito mikanda ya maginito.Ndi njira zowunikira ma cell zomwe zikuchulukirachulukira m'zaka zaposachedwa, mikanda ya maginito imagwira ntchito yofunika kwambiri pakupatula ndikuchotsa ma nucleic acid, monga DNA kapena RNA, kuchokera ku zitsanzo zachilengedwe.Mikanda imeneyi imagwira ntchito ngati zochirikiza zolimba, zomwe zimathandizira kugwira bwino komanso kuyeretsa mamolekyu omwe akufuna.Njira yapamwambayi yathandiza asayansi kupeza zolondola komanso zodalirika, zomwe zimapangitsa kuti pakhale zotsatira zabwino za odwala.
Kuyeretsa Mapuloteni ndi Kusankha Maselo:
Mikanda ya maginito imagwiritsanso ntchito kwambiri pakuyeretsa mapuloteni, njira yovuta kwambiri pakupanga mankhwala ndi kafukufuku wa biochemistry.Mwa kuphatikiza ma ligands ku mikanda, ofufuza amatha kumanga ndikuchotsa mapuloteni omwe ali ndi zoyera komanso zokolola zambiri.Njira yoyeretserayi imafulumizitsa kwambiri kafukufuku wonse, kulola asayansi kusanthula ndi kuphunzira zomanga thupi mwatsatanetsatane.Kusankha ma cell, komwe ndi gawo lofunika kwambiri pazamankhwala ndi kafukufuku, ndi gawo linanso lomwe limapindula kwambiri ndi mikanda ya maginito.Mikanda iyi, yolumikizidwa ndi zolembera kapena ma antibodies, imathandizira kudzipatula ndikuyika magulu osiyanasiyana amagulu.Pogwiritsa ntchito mphamvu ya maginito, asayansi amatha kusanja bwino ndi kulekanitsa maselo potengera momwe amagwirira ntchito.Kusavuta komanso kulondola kwa njirayi kwalimbitsa zoyesayesa zofufuza pakumvetsetsa zovuta zama cell, monga kukula kwa khansa komanso kuyankha kwa chitetezo chamthupi.
Nthawi yotumiza: Jun-25-2023